Virus tricks the body into attacking brain; common heartburn drugs linked to coronavirus risk – Reuters

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FILE PHOTO: A 3D-printed coronavirus design is seen in front of a world map and the words “CoronaVirus Disease (Covid-19)” on screen in this illustration taken March 25, 2020. REUTERS/Dado Ruvic/Illustration

Coronavirus techniques the body into assaulting the brain
Numerous neurological issues such as tremblings, seizures, and impaired awareness have actually been connected to extreme COVID-19, and a little German research study may have uncovered a mechanism by which the infection appears to trick the body into attacking the brain. Scientists have been seeing these symptoms without discovering the coronavirus in the cerebrospinal fluid distributing through the brain and spinal cable. It appears that clients immune systems are producing what are known as autoantibodies that mistakenly target an individuals own tissues or organs, scientists reported on Monday on medRxiv, in advance of peer evaluation. “Remarkably, all 11 patients examined in the present study had strong autoantibodies targeting the brain, which are not typically found in cerebrospinal fluid of healthy individuals,” research study coauthor Dr. Christiana Franke of Charit√© – Universit√§tsmedizin in Berlin told Reuters. The lack of other descriptions for the neurological issues recommends these autoantibodies are to blame, she included. Researchers are working to discover how the coronavirus activates production of autoantibodies, whether other organs are similarly assaulted by the immune system, and whether this likewise occurs as clients are recovering, Franke stated. After the 1918 flu infection pandemic, she kept in mind, around 1 million clients had consistent neurological problems. (bit.ly/ 2VY3AyA).
Heartburn drugs connected to greater coronavirus risk.
Extensively used heartburn drugs that have actually been linked with numerous issues consisting of greater danger for kidney illness and dementia with long-term usage might likewise be connected to a greater risk for COVID-19, researchers have actually found. Researchers carried out a survey of more than 53,000 people, including almost 4,000 who said they had checked positive for COVID-19. “Further studies taking a look at the association between PPIs and COVID-19 are needed,” Spiegels group states.
Inflammation of organs not always tied to viral load in fatal COVID-19.
In fatal cases of COVID-19, the places in the body with the worst inflammation and organ damage are not always the locations with the highest quantity of virus, or viral load, according to a small research study. Autopsies of 11 clients who passed away from COVID-19 showed that some tissues – including the kidney, liver and intestinal tract – consisted of a high quantity of infection however were not swollen, while tissues with irregular or irregular virus levels – in specific, the lungs – were seriously swollen.
Weight problems increases respiratory failure threat in COVID-19.
They studied 1,687 grownups hospitalized with COVID-19, about one in 3 of whom was obese. The findings “support the requirement to consider the community-specific frequency of obesity when preparing a communitys COVID-19 response,” the research team composed on Monday in Annals of Internal Medicine.
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Reporting by Nancy Lapid; Editing by Bill Berkrot.

Various neurological problems such as tremors, seizures, and impaired awareness have been linked to severe COVID-19, and a small German research study may have uncovered a mechanism by which the infection appears to deceive the body into attacking the brain. “Further studies taking a look at the association in between PPIs and COVID-19 are needed,” Spiegels team says. In fatal cases of COVID-19, the locations in the body with the worst swelling and organ damage are not necessarily the locations with the greatest quantity of infection, or viral load, according to a small study. Autopsies of 11 clients who died from COVID-19 showed that some tissues – consisting of the liver, intestine and kidney – contained a high amount of infection however were not inflamed, while tissues with patchy or irregular infection levels – in specific, the lungs – were significantly inflamed. They studied 1,687 grownups hospitalized with COVID-19, about one in 3 of whom was obese.

(Reuters) – The following is a short roundup of a few of the current scientific research studies on the unique coronavirus and efforts to discover treatments and vaccines for COVID-19, the illness brought on by the infection.