COVID-19 and blood type: Whats the link? – Los Angeles Times

Heres an appearance at what researchers have learnt more about blood type and its role in the COVID-19 pandemic.
How lots of blood types are there?

If theres one thing we want to know about COVID-19, its most likely this: Whats my danger of getting it?
Researchers have determined certain things that make some individuals more susceptible than others. Males are at higher risk than women. Older individuals are at greater danger than younger people. Those with persistent illness like Type 2 diabetes, weight problems and severe heart conditions are faring even worse than those without them. Black and Latino Americans are at higher threat than Asian Americans and whites.
Now theres evidence that blood type could be a risk factor too.
A handful of studies have recommended that people with some blood types are more most likely to be hospitalized with COVID-19, while those with other blood types are less most likely to require that level of care. The most current evidence was published last month in the New England Journal of Medicine.

Eight. Yours is determined in part by the presence (or lack) of A and B antigens on your red cell. Your blood type is A if you have just A antigens. Your blood type is B if you have only B antigens. If you have both, your blood type is AB, and if you have neither, your blood type is O.
In addition, red cell may have a protein called Rh aspect. If you have it, youre Rh positive; if not, youre Rh unfavorable.
The mix of A and B antigens and the Rh aspect produces the 8 major blood types: A-positive, A-negative, B-positive, B-negative, AB-positive, AB-negative, O-positive and O-negative.

What did the New England Journal of Medicine research study state about blood types?

If youve been outdoors or can be found in contact with high-touch surfaces, wash your hands for a minimum of 20 seconds. Wear a mask if you leave home and keep a minimum of 6 feet of range in between yourself and others who are not members of your family. Attempt not to touch your face so the infection cant sneak into your body through your eyes, nose or mouth. And make certain to tidy doorknobs, faucets, phones and other regularly touched surfaces every day.
For more suggestions on staying safe, follow this advice from Centers for Disease Control and Prevention.

Another possibility is that the genes connected with blood type also affect the ACE2 receptor on human cells, which the coronavirus looks for and acquires, they wrote.
How can I discover what my blood type is?

At least two other groups have tried to find links in between blood type and COVID-19 risk and discovered similar results.
The very first idea that blood type may have something to do with illness risk can be found in March from scientists in China, who compared 2,173 COVID-19 patients in 3 hospitals in Wuhan and Shenzhen to more than 27,000 “normal individuals.” They discovered that individuals with Type A blood had a 21% higher risk of the disease than their equivalents with other blood types, and that people with Type O blood had a 33% lower threat.

An extra circle on the card consists of antibodies to the protein called Rh factor. A reaction there suggests you are Rh-positive; if nothing occurs, youre Rh-negative.
You can contribute blood if that sounds like too much problem. If go to the Red Cross, theyll send you a donor card that indicates your blood type.

The following month, a group from Columbia University took a look at 1,559 individuals in the New York City location who were evaluated to see whether they were contaminated with the coronavirus that triggers COVID-19. They found that having Type A blood was associated with a 34% greater opportunity of testing favorable, while having Type O blood was connected with a 20% lower possibility of testing positive. In addition, individuals with Type AB blood were 44% less most likely to test positive, although only 21 of the 682 people who tested positive for the coronavirus had AB blood.
The Columbia scientists noted that their findings about the dangers connected with Type A and Type O blood were consistent with the arise from China, even though the distribution of blood types was substantially various in the populations of New York, Wuhan and Shenzhen.
Both of these reports were posted to the MedRxiv website, where scientists share preliminary data prior to it has actually undergone peer evaluation.
Why would blood type have anything to do with COVID-19?

Thats unclear. Perhaps different combinations of A and B antigens alter the body immune systems production of infection-fighting antibodies or have some other unidentified biologic result, the authors of the New England Journal of Medicine study composed.

The research study style did not permit scientists to make any determination about whether blood type was associated with the danger of coronavirus infection, or, if contaminated, the risk of ending up being severely ill.
” The hope is that these and other findings yet to come will point the way to a more extensive understanding of the biology of COVID-19,” Dr. Francis Collins, a geneticist and director of the National Institutes of Health, wrote on his blog. “They also suggest that a hereditary test and an individuals blood type might supply helpful tools for recognizing those who may be at greater risk of major disease.”
How does that line up with other research?

If its been tested in the past, your medical professional may have it on file.
If not, you can evaluate it at home with a set that consists of an Eldoncard. The kit will require you to puncture your finger to acquire a small blood sample, then blend it with antibodies to the A and B antigens that come on the card. If your red cell include A or B antigens, they will react with the antibodies and clump up on the card.
If you only see a response to A antibodies, your blood type is A. Ditto for the B antibodies. If you see a reaction to both, your blood type is AB, and if theres no reaction, your blood type is O.

Everyone should be as mindful as possible all the time, regardless of blood type. (That chooses those with Type O blood too.).

If you have both, your blood type is AB, and if you have neither, your blood type is O.
In this population, having Type A blood was associated with a 45% increased danger of having serious COVID-19. On the other hand, having Type O blood was associated with a 35% decreased danger of the disease. They discovered that having Type A blood was associated with a 34% greater opportunity of screening favorable, while having Type O blood was associated with a 20% lower opportunity of screening positive. In addition, people with Type AB blood were 44% less likely to evaluate favorable, although only 21 of the 682 individuals who evaluated positive for the coronavirus had AB blood.

Scientist examined genetic information from more than 1,600 clients hospitalized with extreme cases of COVID-19 in Italy and Spain and compared them with about 2,200 others who didnt have the illness. After making adjustments to represent the impacts of age and sex on COVID-19 danger, the scientists discovered striking distinctions in blood types of the sick patients compared to the controls.
In this population, having Type A blood was associated with a 45% increased threat of having extreme COVID-19. On the other hand, having Type O blood was associated with a 35% decreased risk of the illness. Those relationships held up whether the Spanish and italian clients were analyzed separately or together.
No other blood groups were related to a greater or lesser threat of the illness. In addition, blood type did not seem to be connected to the threat of requiring to be placed on a mechanical ventilator.